Buy Venlafaxine pills online

How and where to order Venlafaxine (Effexor, Effexor XR) 37.5 mg, 75 mg, 150 mg capsules or tablets online:

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Indications and usage:

Venlafaxine (Effexor, Effexor XR) is a serotonin and norepinephrine reuptake inhibitor (SNRI) indicated for the treatment of adults with:

depression

major depressive disorder

postpartum depression

generalized anxiety disorder

social anxiety disorder

panic disorder

diabetic neuropathy

premenstrual dysphoric disorder

bipolar disorder

borderline personality disorder

obsessive compulsive disorder

vasomotor symptoms

post-traumatic stress disorder

attention deficit-hyperactivity disorder

dissociative identity disorder

irritable bowel syndrome

back pain, chronic pain, fibromyalgia, somatoform pain disorder

vulvodynia

bulimia

cataplexy

autism

sleep disorder

narcolepsy

migraine


Contraindications:

Hypersensitivity to venlafaxine hydrochloride, desvenlafaxine succinate, or any excipients in the drug formulation.

Concomitant use of monoaminoxidase inhibitors or within 14 days of discontinuing an MAOI.


Dosage forms and strengths:

Effexor XR (Venlafaxine) extended-release capsules 37.5 mg, 75 mg, 150 mg.


Dosage and administration:

Maximum Dose	Starting Dose	Target Dose	Maximum Dose
Major depressive disorder	37.5-75 mg/day	75 mg/day	225 mg/day
Generalized anxiety disorder	37.5-75 mg/day	75 mg/day	225 mg/day
Social anxiety disorder	75 mg/day	75 mg/day	75 mg/day
Panic disorder	37.5 mg/day	75 mg/day	225 mg/day

Take once daily with food. Capsules should be taken whole; do not divide, crush, chew, or dissolve.

When discontinuing treatment, reduce the dose gradually.

Renal impairment: reduce the total daily dose by 25% to 50% in patients with renal impairment. Reduce the total daily dose by 50% or more in patients undergoing dialysis or with severe renal impairment.

Hepatic impairment: reduce the daily dose by 50% in patients with mild to moderate hepatic impairment. In patients with severe hepatic impairment or hepatic cirrhosis, it may be necessary to reduce the dose by more than 50%.


Warnings and precautions:

Serotonin syndrome: increased risk when co-administered with other serotonergic agents, but also when taken alone. If it occurs, discontinue venlafaxine and serotonergic agents and initiate supportive treatment.

Elevated blood pressure: control hypertension before initiating treatment. Monitor blood pressure regularly during treatment.

Increased risk of bleeding: concomitant use of aspirin, NSAIDs, other antiplatelet drugs, warfarin, other anticoagulants may increase risk.

Angle-closure glaucoma: angle-closure glaucoma has occurred in patients with untreated anatomically narrow angles, treated with antidepressants.

Activation of mania or hypomania: screen patients for bipolar disorder.

Discontinuation syndrome: taper dose and monitor for discontinuation symptoms.

Seizures: can occur. Use cautiously in patients with seizure disorder.

Hyponatremia: can occur in association with SIADH.

Interstitial lung disease and eosinophilic pneumonia: can occur.

Sexual Dysfunction: Effexor XR may cause symptoms of sexual dysfunction.


Overdosage:

No specific antidotes for venlafaxine capsules and tablets are known. In managing overdosage, consider the possibility of multiple drug involvement. Consider contacting a poison center or a medical toxicologist for overdosage management recommendations.


Side effects, adverse reactions:

Most common adverse reactions of venlafaxine (incidence >= 5% and at least twice the rate of placebo): somnolence, nausea, dry mouth, abnormal ejaculation, sweating, anorexia, men impotence, libido decreased, constipation.

To report suspected side effects of Effexor XR (Venlafaxine) pills contact Pfizer, Viatris pharmaceutical companies, or your local FDA.


Drug interactions:

The concomitant use of SNRIs, including venlafaxine, with Monoamine Oxidase Inhibitors (MAOI) and other serotonergic drugs (including other SNRIs, SSRIs, triptans, tricyclic antidepressants, opioids, lithium, buspirone, amphetamines, tryptophan, and St. John's Wort) increases the risk of serotonin syndrome.

Concomitant use of Effexor with an antiplatelet or anticoagulant drug may potentiate the risk of bleeding.

Concomitant use of a CYP3A inhibitor may increase the risk of toxicity of venlafaxine pills.

The risk of using venlafaxine concomitantly with other central nervous system active drugs drugs (including alcohol) has not been systematically evaluated.

Concomitant use of Venlafaxine (Effexor XR) and weight loss agents is not recommended. The safety and efficacy of therapy in combination with weight loss agents, including phentermine, have not been established.


Usage in specific populations:

Pregnancy

Third trimester use may increase risk for symptoms of poor neonatal adaptation (respiratory distress, temperature instability, feeding difficulty, hypotonia, tremor, irritability) in the neonate.

Lactation

Data from published literature report the presence of venlafaxine and its active metabolite in human milk and have not shown adverse reactions in breastfed infants. There are no data on the effects of venlafaxine on milk production.

Pediatric use

Safety and effectiveness of Effexor XR in pediatric patients have not been established.

Geriatric use

No overall differences in effectiveness or safety were observed between geriatric patients and younger patients, and other reported clinical experience generally has not identified differences in response between the elderly and younger patients.

Hepatic impairment

Dosage adjustment is recommended in patients with mild (Child-Pugh Class A), moderate (Child-Pugh Class B), or severe (Child-Pugh Class C) hepatic impairment or hepatic cirrhosis.

Renal impairment

Dosage adjustment is recommended in patients with mild (CLcr = 60-89 mL/min), moderate (CLcr = 30-59 mL/min), or severe (CLcr < 30 mL/min) renal impairment, and in patients undergoing hemodialysis.


Drug abuse and dependence:

Controlled substance

Venlafaxine is not a controlled substance in most of countries worldwide.

Abuse

While Effexor XR has not been systematically studied in clinical studies for its potential for abuse, there was no indication of drug-seeking behavior in the clinical studies. However, it is not possible to predict on the basis of premarketing experience the extent to which a CNS-active drug will be misused, diverted, and/or abused once marketed. Consequently, providers should carefully evaluate patients for history of drug abuse and follow such patients closely, observing them for signs of misuse or abuse of venlafaxine (e.g., development of tolerance, incrementation of dose, drug-seeking behavior).

Dependence

Effexor XR was not found to have any significant CNS stimulant activity in rodents. In primate drug discrimination studies, venlafaxine showed no significant stimulant or depressant abuse liability.


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Here is a list of popular medications containing venlafaxine as a main active pharmaceutical ingredient; their trade names, forms, doses, companies - manufacturers, distributors, suppliers, researchers and developers:

Trade name of the drug	Pharmaceutical forms and doses	Companies
Efexor	Tablets; Oral; 37.5 mg, 50 mg, 75 mg	Pfizer Wyeth
Effexor	Capsules, Prolonged Release; Oral; 37.5 mg Tablets; Oral; 12.5 mg, 25 mg, 37.5 mg, 50 mg, 75 mg, 100 mg	Pfizer Viatris Wyeth
Effexor XR	Capsules, Extended Release; Oral; 37.5 mg, 75 mg, 100 mg, 150 mg	Pfizer Viatris Wyeth
Venlor	Tablets; Oral; 25 mg, 37.5 mg, 75 mg	Cipla
Venlor XR	Capsules, Extended Release; Oral; 37.5 mg, 75 mg, 150 mg	Cipla